TY  - JOUR
T1  - Simple Cloud Point Extraction‐spectrophotometric for the Determination for Cadmium (II) Using ‐3‐Anilino‐1‐Phenylimino‐Thiourea
AU - Najm, Ali Ihssan
        AU - Alwan, Lilyan
        AU - Jasim, Sura
        
JO  - ACE Journal of Pharmaceutical Sciences
VL  - 5
IS  - 1
SP  - 1
EP  - 7
PY  - 2025
DA  - 2001/08/19
SN  - 2520-5617
DO  - 10.36478/acepharma.2025.1.7
UR  - https://theacepublications.com/article-detail.php?art=272-ACE-JPharma
KW  - Cadmium ion
KW  - Triton X‐114 
KW  -Cloud point extraction
KW  - 3‐anilino‐1‐phenyliminothiourea
AB  - Cadmium (II) was pre‐concentrated through a cloud‐point extraction
(CPE) method after forming a complex with 3‐anilino‐
1‐phenylimino‐thiourea (R.). Triton X‐114, a non‐ionic surfactant, was
employed to facilitate the extraction process, and the resulting
mixture was analyzed by ultraviolet‐visible (UV‐Vis) spectrometry.
Several experimental parameters affecting the efficiency of the CPE
process were optimized, including pH, the concentration of reagent (R),
the volume of Triton X‐114 (0.4 mL), equilibration temperature and time
(55°C), and centrifugation conditions (4,000 rpm for 20 minutes). The
optimal pH was determined to be 4.7, and the extraction was
performed in a 5 mL solution containing 2.5% (v/v) of Triton X‐114 and
1 × 10<sup>‐3</sup> mol∙L<sup>‐1</sup> of (R). Under these optimized conditions, the method achieved a limit of detection (LOD) for cadmium (II) of 0.0091 μg∙mL<sup>‐1</sup> and a limit of quantification (LOQ) of 0.02 μg∙mL<sup>‐1</sup>. The linearity of the calibration curve was maintained over the concentration range of 0.012 to 3.0 μg∙mL<sup>‐1</sup>. The method also demonstrated good precision, with a relative standard deviation (RSD) of 6.3% for seven replicates (n = 7) at a cadmium (II) concentration of 6.3 μg∙mL‐1.
ER  -