TY  - JOUR
T1  - Investigation of Fertility Promoting Effect of Typha Capensis in Male Rats
AU - Sachit, Muhaned
        AU - Obaid, Sarah
        AU - Mohammed, Makarim
        
JO  - ACE Journal of Public Health and Community Medicine
VL  - 4
IS  - 2
SP  - 42
EP  - 47
PY  - 2024
DA  - 2001/08/19
SN  - 2520-5633
DO  - acejphcm.2024.42.47
UR  - https://theacepublications.com/article-detail.php?art=229-ACE-JPHCM
KW  - Typha Capensis Infertility
AB  - One of the medicinal plants frequently used to manage health with male fertility is Typha
capensis. The aim of the present study was to investigate at how it impacted fertility in a
rat model of cadmium?induced infertility. In this experiment, 30 male rats weighing 150
to 250 g were employed. The animals divided into five groups, six male rat of each as;
group A: was treated with 0.5ml normal saline solution only. Group B: treated with CdCl2
(2.5mg/kg) and 0.5 ml of normal saline (NaCl2 0.9%) solution served as control group.
Group C: treated with CdCl2 (2.5mg/kg) plus T. capensis extract at 120 mg/kg. Group D:
treated with CdCl2 (2.5mg/kg) plus T. capensis extract at 200 mg/kg and Group E: CdCl2
(2.5mg/kg) plus T. capensis extract at 400 mg/kg. Gavage was used once a day for 28 days
to treat the animals orally. The animals were sacrificed through carbon dioxide sedation
after 28 days. The testes and epididymis were harvested through an abdominal midline
incision. All clinging tissues were removed, the swollen dried the weights were taken
promptly. Histological assessment of the samples was conducted. the absolute weight of
testes and epididymis of experimental animals improved by treating with T. capensis
significantly (p<0.05) differences between group A, D and E when compare with group A
that served as control group, whereas group C showed no?significant variance in
comparison with group A. The group treated with T. capensis extract demonstrated high
sperm counts in comparison to the CaCl2?treated control group, for group treated with
extract doses 120, 200 and 400 mg/kg, respectively, with highly significant differences
between group D and E in comparison with group B as a control group, whereas the results
exhibited non?significant differences between group C treated with 120mg/kg of extract
in comparison with group B control. The results also show significantly higher increase in
sperm count at group A saline group in comparison with group B control. Our findings
showed that T. capensis had significant protective effects with concentration of (200 and
400 mg/kg of TCE) that resulted in optimal sperm production when comparison with
control group. The current study's findings demonstrate that T. capensis was able to
prevent infertility induced oxidative stress caused on by CaCl2 treatment. Histological
examinations show a significant form of protection against cadmium?induced tissue
necrosis, which was sufficient to result in increased sperm production.
ER  -