@article{ACEJPHCM202442228,
    title = {ROS Influence in Oral Ulcer Occurrence, Number and Types in Systemic Lupus Erythematosus Patients},
    journal = {ACE Journal of Public Health and Community Medicine},
    volume = {4},
    number = {2},
    pages = {37-41},
    year = {2024},
    issn = {2520-5633},
    doi = {acejphcm.2024.37.41},
    url = {https://theacepublications.com/article-detail.php?art=228-ACE-JPHCM},
    author = {Mohammed},
    keywords = {ROS, Oral ulcer occurrence Number Systemic lupus erythematosus Patients},
    abstract = {Systemic lupus erythematosus (SLE) is an autoimmune disease
characterized by oral ulcer (Ou) as one of the SLE manifestations, some
factors are contributed in SLE etiology, Reactive oxygen species (ROS)
are one of these factors. A cross sectional study aim to evaluate the ROS
role in oral ulcer occurrence, number and types in SLE patients. The
results demonstrate significant changes in age, non?sig in BMI and
patients duration average was 6.87 years. The ROS level showed
significant?elevation in SLE group (p = 0.000). Patients classified
according to oral ulcer occurrence results found high percentage of
patients have Ou (72.60)% with non?sig changes in age, BMI, duration
and ROS level. finding also showed (48.4%) of patients have single Ou,
low percentage (24.3%) have multiple Ou and (27.4%) without Ou with
non?sig changes in all study variation and slightly elevation of ROS in a
single ulcer, five types of oral ulcer including mouth, lips, tongue,
pharynx and gum, high percent of patients have mouth ulcer (33.9%),
then tongue (14.5%) and low percent was observed in lips (3.9%) and
variables have non?sig changed, ROS was elevated in mouth Ou and
decreased in lips oral Ou, other types have slightly changes in compare
with patients without Ou, The ROS levels in each oral ulcer types in
compare with patient without this types didn’t significant associated
with ROS levels (p = 0.143, 0.366, 0.394, 0.471, 0.729) for mouth, lips,
tongue, pharynx and gum respectively. the current finding proved robust
association of SLE with ROS level but non?significant relation with oral
ulcer incidence, type and number in SLE patients.}
    }